Osteosarcoma and soft-tissue sarcomas with an immune infiltrate express PD-L1: relation to clinical outcome and Th1 pathway activation

Immune checkpoint proteins, such as PD-L1 and PD-1, are important in several cancers; however, their role in osteosarcoma (OSA) and soft tissue sarcoma (STS) remains unclear.Our aims were to determine whether subsets of OSA/STS harbor tumor-infiltrating lymphocytes (TILs) and express PD-L1, and how PD-L1 expression Counter Height Stool is related t

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RELATIONSHIP BETWEEN ANXIETY LEVELS WITH SLEEP QUALITY IN PRIMIGRAVIDA THIRD-TRIMESTER PREGNANCY AT JEUMPA MATERNITY HOSPITAL PONTIANAK

Background Anxiety is an emotional condition characterized by tension, fear and anxiety, accompanied by somatic symptoms (headache, sweating, palpitation, chest tightness, and mild stomach upset), which is one of the psychological aspect affecting pregnancy, especially primigravida pregnancy.Anxiety stimulates the body to be difficult to relax in p

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